Synthetic copper peptide researched for hair follicle stimulation, VEGF angiogenesis, and collagen production.
Peptigrity tracks AHK-Cu across 219 shops with 11 independent lab tests and an average HPLC purity of 99.55%.
AHK-Cu (Copper Tripeptide-3) is a synthetic copper-complexed tripeptide composed of alanine, histidine, and lysine coordinated with a Cu²⁺ ion. Unlike the naturally occurring GHK-Cu (which focuses on broad skin repair and collagen synthesis), AHK-Cu is specifically designed to target hair follicle biology. Published research (Pyo et al., Archives of Pharmacal Research, 2007) demonstrated stimulation of hair follicle elongation and dermal papilla cell proliferation in human tissue models. Key mechanisms include upregulation of vascular endothelial growth factor (VEGF) for new blood vessel formation around follicles, reduction of TGF-β1 secretion to counteract DHT-mediated hair growth inhibition, and enhancement of superoxide dismutase (SOD) production to reduce oxidative stress in scalp follicles. Used in cosmetic formulations at 0.3–1% concentration. Molecular weight: approximately 403.9 Da (peptide portion).
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