Enter the vial size and the bacteriostatic water you added to get the concentration and the micrograms carried by each unit on a U-100 syringe. PEG MGF has no published human efficacy trial and no stated dose, so this page does the arithmetic, not the recommendation. The compound itself is covered in the PEG MGF guide.
A 2 mg vial of PEG MGF reconstituted with 2 mL of bacteriostatic water gives a concentration of 1.0 mg/mL, or 10 mcg per unit on a U-100 syringe.
Defaults: 2 mg is the most common labelled vial among the PEG MGF tests on file, 21 Sep 2026 (13 of 28); 2 mL was chosen for simple arithmetic and is not a sourced volume. Peptigrity publishes no PEG MGF dose, so the dose field starts empty.
Draw the syringe up to
Enter your own amount to see the draw. Add 2 mL of water to your 2 mg vial first.
PEG MGF has 28 independent lab tests on file at Peptigrity, averaging 99.39% HPLC purity across the tests that report one. Purity is not net content: a clean certificate confirms what is in a vial, not how much. See the PEG MGF lab-test records.
PEG MGF is mechano growth factor — a splice variant of IGF-1 expressed in muscle in response to mechanical loading — with polyethylene glycol (PEG) chains attached, which the compound page says extends its half-life from minutes to approximately 2–6 days. The evidence is preclinical: satellite-cell activation and muscle repair in rodent models. There are no published Phase 2 or Phase 3 efficacy trials in humans as of August 2026, so there is no studied quantity to cite, and the compound page declines to state one.
The table summarises what the PEG MGF compound page states (last updated August 2026).
| Question | What the compound page states | Evidence level |
|---|---|---|
| What is it? | PEGylated mechano growth factor, a modified splice variant of IGF-1 | Chemical identity |
| Half-life? | Approximately 2–6 days, against minutes for native MGF | As stated; preclinical basis |
| Human studies? | No published Phase 2 or Phase 3 efficacy trials (as of August 2026) | Preclinical |
| An approved dose? | Not approved for any medical indication anywhere in the world (as of August 2026) | None |
| A research dose? | None stated; no route stated either | None — declined |
One practical consequence: the compound page notes that the PEG chain length can vary by batch and vendor, which makes the molecular weight vary too, and that some vendors sell native MGF labelled as PEG MGF. The arithmetic below converts the milligrams on a label into units; it cannot tell you which molecule, or which PEG chain, is in the vial. Only mass spectrometry — interpreted for a PEG conjugate's distinct distribution pattern — can.
PEG MGF is not IGF-1 LR3: it acts through the MGF receptor, a splice variant of IGF-1R, on local muscle repair, where IGF-1 LR3 is systemic IGF-1R activation. The two have separate calculators; the other one is the IGF-1 LR3 calculator.
The table converts reference quantities to syringe units at the default of 1.0 mg/mL (2 mg of PEG MGF in 2 mL), and counts how many draws of each a vial holds. Every row is arithmetic, not a dose: read the units for the amount you already intend to measure.
| Quantity | Draw at 1.0 mg/mL | Volume | Draws from a 1 mg vial | Draws from a 2 mg vial |
|---|---|---|---|---|
| 20 mcg | 2.0 units | 0.02 mL | 50 | 100 |
| 50 mcg | 5.0 units | 0.05 mL | 20 | 40 |
| 100 mcg | 10.0 units | 0.10 mL | 10 | 20 |
| 200 mcg | 20.0 units | 0.20 mL | 5 | 10 |
| 500 mcg | 50.0 units | 0.50 mL | 2 | 4 |
The same PEG MGF quantity lands on a different mark depending on how much water went into the vial. Read down the column for the concentration you actually mixed; a units figure carried across from another column is simply wrong.
| Quantity | At 2.0 mg/mL (2 mg + 1 mL) | At 1.0 mg/mL (2 mg + 2 mL) | At 0.40 mg/mL (2 mg + 5 mL) |
|---|---|---|---|
| 20 mcg | 1.0 units | 2.0 units | 5.0 units |
| 50 mcg | 2.5 units | 5.0 units | 12.5 units |
| 100 mcg | 5.0 units | 10.0 units | 25.0 units |
| 200 mcg | 10.0 units | 20.0 units | 50.0 units |
| 500 mcg | 25.0 units | 50.0 units | — over a 1 mL barrel (125 units) |
Every cell is the same arithmetic: units = (quantity in mg ÷ concentration in mg/mL) × 100 on a U-100 syringe. More water spreads the same mass over more units, which is the fix when a small quantity would otherwise sit at two or three units, where a one-unit misread is a large error.
Each PEG MGF vial holds as many draws as its labelled mass divided by the quantity per draw; the water volume changes nothing about it. The grid counts draws, not weeks — this page states no frequency.
| Vial size | At 20 mcg | At 50 mcg | At 100 mcg | At 200 mcg | At 500 mcg |
|---|---|---|---|---|---|
| 1 mg | 50 | 20 | 10 | 5 | 2 |
| 2 mg | 100 | 40 | 20 | 10 | 4 |
| 5 mg | 250 | 100 | 50 | 25 | 10 |
The labelled mass is not a guarantee of the mass in your vial: net content is a separate measurement from purity, and certificates on file often measure a few percent above or below the label.
No label sets a diluent volume for research-grade PEG MGF, and the compound page states none, so the volume is a choice. PEG MGF vials are small (this calculator offers 1, 2 and 5 mg), so the usual resolution problem runs both ways: too little water and a small quantity sits at one or two units, where a one-unit misread is a large error; too much and a larger quantity no longer fits in one 1 mL barrel. The technique is covered once, elsewhere: reconstituting peptides step by step and the bacteriostatic water guide. Storage and in-use guidance there is general peptide guidance, not a PEG MGF-specific finding.
PEG MGF is not approved for any medical indication anywhere in the world as of August 2026, and no active clinical development program is advancing. On the compounding side, PEG-MGF (as "Mechano Growth Factor, Pegylated") was one of twelve peptides the FDA removed from its Category 2 bulk-substances list in April 2026 — a change the FDA attributed to the nomination being withdrawn, not a safety clearance, and one that did not add PEG-MGF to Category 1 or authorize compounding. It is one of five of those peptides slated for separate Pharmacy Compounding Advisory Committee consideration before the end of February 2027; until the FDA completes any rulemaking, PEG-MGF remains research-use-only with no legal compounding pathway. For tested athletes, the World Anti-Doping Agency's Prohibited List names "Mechano growth factors (MGFs)" under Section S2.3, prohibited at all times.
Independent test records: PEG MGF lab tests. Tracked prices: PEG MGF price per milligram. The IGF-family neighbour: IGF-1 LR3 guide and IGF-1 LR3 calculator.
It depends on the concentration. At the page default of 1 mg/mL (a 2 mg vial with 2 mL of water), each unit on a U-100 syringe carries 10 mcg, so 100 mcg is 10 units (0.10 mL). With 1 mL in the same vial (2 mg/mL) it is 5 units. A units figure quoted without a concentration cannot be used.
There isn't one. PEG MGF has no published Phase 2 or Phase 3 human efficacy trial, is not approved for any medical indication, and Peptigrity does not recommend a dose. This calculator converts a quantity you already have in mind into syringe units; it does not supply the quantity.
No. MGF is a splice variant of IGF-1 with a unique C-terminal extension, expressed in muscle in response to mechanical loading, and it binds a distinct receptor (the MGF receptor, a splice variant of IGF-1R). PEG MGF is the PEGylated version of native MGF. IGF-1 LR3 has its own calculator.
No. It converts the labelled mass into units. The compound page notes that some vendors sell native MGF labelled as PEG MGF and that PEG chain length varies by batch; only mass-spectrometry identity confirmation on a certificate can tell them apart.
Yes. The World Anti-Doping Agency's Prohibited List names Mechano growth factors (MGFs) explicitly under Section S2.3, prohibited at all times — the same subsection that lists IGF-1 and its analogues.