Calculate exact syringe units for your BPC-157 + TB-500 “Wolverine” blend vial. Enter each peptide's milligrams, BAC water volume, and target dose - the calculator shows the precise draw plus every other peptide's dose per injection. Covers 1:1 and 1:2 ratio blends with loading and maintenance protocols.
Enter amounts for all peptides, BAC water volume, and target dose to see results.
The Wolverine stack combines BPC-157 (local repair via VEGF, nitric oxide, GH receptor pathways) with TB-500 (systemic repair via actin regulation and cell migration). The protocol typically uses a loading phase followed by a maintenance phase.
| Intensity | BPC-157 | TB-500 | Frequency | Duration |
|---|---|---|---|---|
| Standard loading | 500 mcg | 750-1,000 mcg | 1× daily | 2-4 weeks |
| Aggressive loading | 500 mcg | 2,000 mcg | 2× daily | 1-2 weeks |
| Conservative loading | 250 mcg | 500 mcg | 1× daily | 4 weeks |
| BPC-157 | TB-500 | Frequency | Duration |
|---|---|---|---|
| 250 mcg | 500 mcg | 1× daily | 4-8 weeks |
| 250 mcg | 750 mcg | 5 on / 2 off | 6-8 weeks |
For the complete protocol breakdown, see the Wolverine stack guide.
| Blend Vial | BAC Water | BPC Conc. | TB Conc. | 250 mcg BPC Draw |
|---|---|---|---|---|
| 5 mg BPC + 5 mg TB | 2 mL | 2.5 mg/mL | 2.5 mg/mL | 10 units (+ 250 mcg TB) |
| 5 mg BPC + 10 mg TB | 2 mL | 2.5 mg/mL | 5 mg/mL | 10 units (+ 500 mcg TB) |
| 10 mg BPC + 10 mg TB | 4 mL | 2.5 mg/mL | 2.5 mg/mL | 10 units (+ 250 mcg TB) |
| 10 mg BPC + 20 mg TB | 4 mL | 2.5 mg/mL | 5 mg/mL | 10 units (+ 500 mcg TB) |
Common blend ratios: 1:1 (equal mg BPC and TB) or 1:2 (double TB-500). The ratio determines how much TB-500 you receive per BPC-157 dose. Use the calculator above to see the exact per-peptide breakdown for your vial.
If using separate vials rather than a blend, TB-500 is typically supplied in 5 mg or 10 mg standalone vials.
| Vial | BAC Water | Conc. | 500 mcg Draw | 1 mg Draw | 2 mg Draw |
|---|---|---|---|---|---|
| 5 mg | 1 mL | 5 mg/mL | 10 units | 20 units | 40 units |
| 5 mg | 2 mL | 2.5 mg/mL | 20 units | 40 units | 80 units |
| 10 mg | 2 mL | 5 mg/mL | 10 units | 20 units | 40 units |
For standalone BPC-157 reconstitution, see the BPC-157 calculator.
| Property | BPC-157 | TB-500 |
|---|---|---|
| Full name | Body Protection Compound-157 | Thymosin Beta-4 fragment (Tβ4₁₇₋₂₃) |
| Amino acids | 15 | 43 |
| Molecular weight | 1,419.53 Da | ~4,963 Da |
| Primary mechanism | VEGF, nitric oxide, GH receptor | Actin regulation, cell migration |
| Action type | Local (inject near injury) | Systemic |
| Oral viability | Yes (acid stable for GI targets) | No |
| Common dose | 250-500 mcg 1-2× daily | 500-2,000 mcg 1× daily |
| Typical cycle | 4-8 weeks | 6-12 weeks |
| Blend Vial | 250 mcg BPC 1×/day | 500 mcg BPC 1×/day | 500 mcg BPC 2×/day |
|---|---|---|---|
| 5 mg BPC + 5 mg TB | 20 days ✅ | 10 days ✅ | 5 days ✅ |
| 10 mg BPC + 10 mg TB | 40 days ⚠️ | 20 days ✅ | 10 days ✅ |
| 10 mg BPC + 20 mg TB | 40 days ⚠️ | 20 days ✅ | 10 days ✅ |
Vial duration is determined by whichever peptide runs out first (in equal-ratio blends, both run out simultaneously). See how to store peptides.
A quality Wolverine blend should show two distinct HPLC peaks - BPC-157 at MW 1,419.53 Da and TB-500 at approximately 4,963 Da. Mass spec should confirm both weights. Check that the stated peptide quantities match - underdosing is more common in blends than single-peptide vials. Cross-reference with independent lab test results.
| Tool | What It Does |
|---|---|
| BPC-157 Calculator | Standalone BPC-157 with injury-type protocols |
| Blend Calculator | Any multi-peptide blend vial |
| Peptide Reconstitution Calculator | Standard calculator for individual vials |
| Reverse Calculator | Convert units to mg, verify doses |
| Cost-per-Dose Calculator | Compare Wolverine stack costs |
| BAC Water Calculator | Optimal BAC water for target concentration |
The Wolverine stack is BPC-157 + TB-500. BPC-157 acts locally through VEGF and NO pathways while TB-500 acts systemically through actin regulation. They target complementary tissue-repair mechanisms.
Use the calculator above. Enter your vial's peptide amounts, BAC water, and choose which peptide to dose based on. The calculator shows exact syringe units and per-peptide breakdown per draw.
Loading (2-4 weeks): higher doses to initiate repair - e.g. 500 mcg BPC + 750-2,000 mcg TB daily. Maintenance (4-8 weeks): reduced doses - e.g. 250 mcg BPC + 500 mcg TB daily.
Blend vials are convenient (single draw) but have a fixed ratio. Separate vials allow independent dose adjustment and different injection sites (BPC near injury, TB in abdomen).
6-12 weeks total: 2-4 weeks loading + 4-8 weeks maintenance. A 2-4 week break between cycles is recommended.
In a blend vial, both are in the same draw - injected together by definition. From separate vials, some protocols inject BPC-157 near the injury and TB-500 in the abdomen for combined local + systemic effect.
Community consensus says yes - they target complementary repair pathways. BPC-157 is local (VEGF, NO) while TB-500 is systemic (actin, cell migration). No controlled human comparison trials exist.
This calculator is for educational and research purposes only and does not constitute medical advice. BPC-157 and TB-500 are investigational compounds not approved by the FDA for human use. Preclinical data referenced herein is from animal models. Always consult a qualified healthcare provider. Peptigrity is an independent review platform and does not sell, endorse, or recommend specific products or vendors.